Valery V. Cheranev

This study evaluates pharmacogenomic data in Russian children and newborns, highlighting the need for age-adjusted interpretation and developing a pediatric pharmacogenomics reporting model.

The paper identifies monogenic variants in the Russian population associated with adverse drug reactions, highlighting their potential to improve personalized pharmacotherapy.

The paper analyzes pharmacogenomic variants in 6,102 Russian exomes, identifying key drug metabolism and toxicity-related variants and highlighting limitations of WES for non-coding variant imputation.

This study compares four exome enrichment kits, finding high coverage and variant calling accuracy, with Nanodigmbio showing highest precision and Vazyme and Nanodigmbio comparable to Agilent and Roche.

This study identifies genetic variants associated with IgA nephropathy in pediatric patients through an exome-wide association analysis.

This study compares Agilent SureSelect All Exon v8 and v7 probes for exome sequencing, finding v8 improves SNV and indel detection with the same read count.

The paper identifies and addresses common pitfalls in DIY RNA-seq library preparation, offering guidance to improve workflow success.

The paper compares a new WES protocol, RSMU_exome, to an existing MGI Tech kit, showing it detects more variants with higher sensitivity and specificity while being cheaper and allowing more samples to be pooled.

The paper investigates the association between HLA alleles and COVID-19 mortality in the Russian population using high-resolution sequencing and statistical analysis.