Maria Isabel Carreño-Muñoz

This study shows that mTORC1 dysregulation in PV interneurons affects tactile sensitivity and social behavior by altering connectivity and excitability.

This study shows that sub-anesthetic ketamine reduces deviant detection responses in auditory cortex and posterior parietal cortex, affecting cellular, population, and mesoscale levels.

This study shows that p75NTR upregulation after perinatal hypoxia impairs PV GABAergic cell maturation and leads to cognitive deficits in adult mice, which can be reversed by p75NTR inhibition.

This study shows that p75NTR in adolescent PV interneurons affects adult cognitive flexibility by altering PV cell connectivity and perineuronal net formation.

This study identifies sensory processing dysregulations in SYNGAP1 haploinsufficiency in mice and humans, suggesting they as potential translational biomarkers.