NeuroscienceFrontiers in Aging NeurosciencePeer-reviewed
Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice
Allen L. Pan, Mickaël Audrain, Emmy Sakakibara…·Stephen R. Salton
This study shows that DUSP6 overexpression in the dorsal hippocampus of male 5xFAD mice reduces amyloid load and improves memory, while also reducing neuroinflammation in both sexes.
9 citations