Author

Philippe Pourquier

InsermORCID 0000-0001-5326-3005Unclaimed ORCID profile · follow to get notified of new preprints

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Philippe Pourquier1 paper

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Céline GongoraiD· 2 shared Abdelhay BoulahtoufiD· 1 shared Adeline TorroiD· 1 shared Alexandre Evrard· 1 shared Alice MatheuxiD· 1 shared Amélie Gudin-de-ValleriniD· 1 shared Aurélie GennetieriD· 1 shared Benoît MiottoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Céline GongoraORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 4, 2026

The Pregnane X Receptor (PXR) contributes to phenotypic plasticity and modulates the sensitivity to targeted therapies in melanoma

Stefan D Nicolescu, Alice Matheux, Marina Grimaldi…·Philippe Pourquier

This study shows that PXR expression in melanoma cells increases sensitivity to BRAFi/MEKi treatment and is linked to a melanocytic phenotype.

DOI 10.64898/2026.11.03.762858

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 11, 2025

Targeting SUV4-20H epigenetic enzymes as therapeutic strategy for enhancing topoisomerase II poisoning in prostate cancer

Fatima Alhourani, Marine Tauziet, Julie Patouillard…·Eric Julien

This study shows that inhibiting SUV4-20H enzymes enhances the effectiveness of TOP2 poisons in prostate cancer by increasing DNA damage and impairing repair mechanisms.

DOI 10.1101/2025.03.11.642623

humanbulk RNA-seq

𝕏 PostBluesky