Zheng Liu

This paper designs a stable, high-affinity CR2 binder using deep learning to enhance B cell activation as a vaccine scaffold.

This study identifies the structural basis for PINK1 maturation by the HSP90/CDC37/FKBP51 chaperone complex and shows FKBP51 negatively regulates PINK1 function in mitophagy.

This study identifies conformational dynamics and dimer formation in TcPINK1, showing their role in Parkin recruitment and mitophagy.

The paper identifies disease-specific metabolic biomarkers for coronary heart disease, diabetes mellitus, and their co-occurrence using metabolomics profiling and statistical analysis.

MitoStructSeg accurately segments mitochondrial structures and quantifies morphological features in human and mouse tissues using a deep learning framework.

This study evaluates metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid for diagnosing central nervous system infections, finding it detects pathogens in 36.6% of cases with some false positives and negatives.