Emre Caglayan

The paper compares somatic mutation rates and transcriptomic changes in neurons across six mammalian species, finding higher mutation accumulation and distinct age-related dysregulation in human neurons.

The paper identifies evolutionary patterns in the human brain epigenome using single-cell ATAC-seq data, revealing lineage-specific regulatory changes and their association with brain disease variants.

The paper compares snRNA-seq data across species to identify cellular differences in the striatum, finding novel interneuron types in bats and differences in neuron-to-glia ratios between primates and non-primates.

The paper uses spatial single-cell analysis to uncover molecular and structural development of human fetal cortex, revealing early layer and area specification.

The paper analyzes ambient RNA contamination in brain single-nuclei RNA-seq, showing it misclassifies cell types and reveals previously undetected oligodendrocyte progenitor cells after correction.

This study identifies genes linked to brain activity that show disrupted associations in autism spectrum disorder, highlighting excitation-inhibition imbalance and regional effects.

This paper links brain oscillations to gene expression in human patients, identifying gene modules associated with memory encoding and neuropsychiatric disorders.