Monica Devi Manam

The paper compares somatic mutation rates and transcriptomic changes in neurons across six mammalian species, finding higher mutation accumulation and distinct age-related dysregulation in human neurons.

The paper analyzes somatic mutations in cerebellar granule neurons and finds distinct mutation patterns compared to other neuronal types, suggesting links to cancer origins and neurodegeneration.

This study benchmarks six duplex sequencing technologies to evaluate their performance in detecting somatic mutations across different genomic contexts and tissue types.

The paper uses spatial single-cell analysis to uncover molecular and structural development of human fetal cortex, revealing early layer and area specification.