Yuxiang Liu

This paper identifies UNC5B-AS1, a super enhancer-driven lncRNA, as a regulator of inflammatory phenotypic transition in PASMCs under hypoxia, showing its role in stabilizing mitochondrial complex IV interactions and modulating lactylation of inflammatory gene promoters.

This study identifies SIK3 T221 phosphorylation as an indicator and controller of sleep need, showing reduced sleep need in mutants and after sleep deprivation.

This study identifies calcineurin as a phosphatase that dephosphorylates SIK3 at specific sites, linking it to sleep regulation in mice.

This study shows that human CLOCK has extra-circadian functions in the neocortex, enhancing cognitive flexibility and neural connectivity through altered gene expression in excitatory neurons.

The paper analyzes ambient RNA contamination in brain single-nuclei RNA-seq, showing it misclassifies cell types and reveals previously undetected oligodendrocyte progenitor cells after correction.