Jelmer Vlasma

A repair-associated bronchial epithelial differentiation trajectory through KRT14+ basal and hillock-like cells drives airway inflammation and remodelling in childhood-onset asthma

The paper identifies a novel asthma-associated epithelial differentiation trajectory involving KRT14+ basal cells and hillock-like cells that contributes to airway inflammation and remodelling in childhood-onset asthma.

Receptor agonist of NFκB signaling ligand directs lung epithelial cell expansion through RANK signaling

This study shows RANKL promotes alveolar epithelial cell expansion in mice and humans, suggesting RANKL/RANK signaling as a conserved pathway for lung tissue repair.

Myeloid cell differentiation within extracorporeal membrane oxygenators in patients with ARDS

The paper uses single-cell RNA sequencing to identify myeloid cell retention and differentiation in extracorporeal membrane oxygenators of ARDS patients, linking it to potential MO dysfunction.