Author

Akshaya Keerthi Saikumar Jayalatha

University Medical Center GroningenORCID 0000-0003-4670-4540Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Gerard H. KoppelmaniD· 2 shared Judith M. VonkiD· 2 shared Maarten van den BergeiD· 2 shared Martijn C. NawijniD· 2 shared Sharon Brouwer· 2 shared A Alexandros Imprachim· 1 shared Aleksandra BalwierziD· 1 shared Alexandra B. FirsovaiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

Gerard H. KoppelmanORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 24, 2026

A repair-associated bronchial epithelial differentiation trajectory through KRT14+ basal and hillock-like cells drives airway inflammation and remodelling in childhood-onset asthma

Tessa E. Gillett, Aurore C. A. Gay, Jelmer Vlasma…·Martijn C. Nawijn

The paper identifies a novel asthma-associated epithelial differentiation trajectory involving KRT14+ basal cells and hillock-like cells that contributes to airway inflammation and remodelling in childhood-onset asthma.

DOI 10.64898/2026.09.16.752044

humanscRNA-seq

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ImmunologyNature ImmunologyPeer-reviewedFeb 17, 2026

Single-cell multiomics of pediatric BM reveals age-dependent differences in lineage differentiation linked to stromal cell heterogeneity

Evelyn S. Hanemaaijer, Konradin F. Müskens, Ireen J. Kal…·Mirjam E. Belderbos

The paper generates a single-cell multi-omics atlas of pediatric bone marrow, revealing age-related shifts in lineage differentiation linked to stromal cell heterogeneity.

8 citationstop 1%

humanscRNA-seq

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Molecular BiologybioRxivPreprintOct 20, 2022

IL-33 induced gene expression in activated Th2 effector cells is dependent on IL-1RL1 haplotype and disease status

Akshaya Keerthi Saikumar Jayalatha, Marlies E. Ketelaar, L Hesse…·Martijn C. Nawijn

The paper investigates how IL-33-induced gene expression in Th2 cells depends on IL-1RL1 haplotype and asthma status, finding stronger effects in risk haplotype carriers and a correlation with pauci-granulocytic asthma.

2 citations

humanbulk RNA-seq

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