Author

Jonathan W. Mount

Icahn School of Medicine at Mount SinaiORCID 0000-0001-5366-0449Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Avner SchlessingeriD· 1 shared Ha NguyeniD· 1 shared Ian W. GlaaseriD· 1 shared Keino HutchinsoniD· 1 shared Paul A. SlesingeriD· 1 shared Peng YuaniD· 1 shared Yihan ZhaoiD· 1 shared Yulin ZhaoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

Avner SchlessingerORCID

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1 paper

Recent·Most cited

Key residue Unlocks Dual PIP2-Dependent and Independent Gating in G Protein-Gated Inwardly Rectifying Potassium Channels

Ha Nguyen, Jonathan W. Mount, Keino Hutchinson, Yihan Zhao, Yulin Zhao, Ian W. Glaaser, Peng Yuan, Avner Schlessinger, Paul A. Slesinger

The paper identifies R92 as a key residue in GIRK2 channels that modulates both PIP2-dependent and independent gating mechanisms through experimental and structural analyses.

bioRxiv · Feb 14, 2025 · PreprintBiophysics