Author

Tialfi Bergamin de Castro

University of Maryland, BaltimoreORCID 0000-0001-5366-7229Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alison J. ScottiD· 1 shared Ciaran M. SkerryiD· 1 shared David M. RickertiD· 1 shared Elizabeth Hill· 1 shared Karen M. ScanloniD· 1 shared Neal S. SilvermaniD· 1 shared Neeta Rajbanshi· 1 shared Nicholas H. CarbonettiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Alison J. ScottORCID

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1 paper

Recent·Most cited

B. pertussis, tracheal cytotoxin biases NOD signaling to suppress IL-1 mediated inflammation and evade adaptive immunity

David M. Rickert, Elizabeth Hill, Riley Himmelberger, Neeta Rajbanshi, Sasha Cardozo, Tialfi Bergamin de Castro, Ravi Bharadwaj, Alison J. Scott, Neal S. Silverman, William E. Goldman, Nicholas H. Carbonetti, Karen M. Scanlon, Ciaran M. Skerry

This study shows that B. pertussis releases tracheal cytotoxin (TCT), which biases NOD1 over NOD2 signaling, suppresses IL-1β inflammation, and evades adaptive immunity.

bioRxiv · Aug 8, 2025 · PreprintMicrobiology