Author

Neal S. Silverman

University of Massachusetts Chan Medical SchoolORCID 0000-0002-4259-456XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alison J. ScottiD· 1 shared Ciaran M. SkerryiD· 1 shared David M. RickertiD· 1 shared Elizabeth Hill· 1 shared Evan Stuart BradleyiD· 1 shared Jennifer P WangiD· 1 shared Karen M. ScanloniD· 1 shared Katherine A. FitzgeraldiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Alison J. ScottORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 8, 2025

B. pertussis, tracheal cytotoxin biases NOD signaling to suppress IL-1 mediated inflammation and evade adaptive immunity

David M. Rickert, Elizabeth Hill, Riley Himmelberger…·Ciaran M. Skerry

This study shows that B. pertussis releases tracheal cytotoxin (TCT), which biases NOD1 over NOD2 signaling, suppresses IL-1β inflammation, and evades adaptive immunity.

5 citations

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologyMicrobiology SpectrumPeer-reviewedJan 31, 2025

CRISPR editing of candidate host factors that impact influenza A virus infection

Pyae Phyo Kyawe, Ping Liu, Zhaozhao Jiang…·Jennifer P Wang

This paper uses CRISPR to test host factors affecting influenza A virus infection, finding that CMAS knockout and B4GALNT2 overexpression restrict IAV, while ADAR1 overexpression has a pro-viral effect on CVB.

3 citations

humangenetic perturbation / CRISPR

𝕏 PostBluesky