Federica Ungaro

The paper evaluates segmentation methods for reconstructing cell-like profiles from spatial transcriptomics data but finds no reliable method under the given constraints.

This study introduces TES, an epigenetic silencer targeting YAP/TAZ-TEAD axis in GBM, which suppresses tumor growth and invasiveness while being safe for normal cells.

The paper shows that SET levels influence enhancer usage during cell fate acquisition, leading to altered gene regulation and contributing to disease.