Author

Stephanie W. Tam

Memorial Sloan Kettering Cancer CenterORCID 0000-0001-5395-9408Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Assay:electrophysiology· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Kate HufferiD· 1 shared Kenton Jon SwartziD· 1 shared Mufeng Li· 1 shared Stephen Barstow LongiD· 1 shared Swati PantiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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1 shared paperNeuroscience

Kate HufferORCID

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2 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedApr 18, 2025

The pentameric chloride channel BEST1 is activated by extracellular GABA

Swati Pant, Stephanie W. Tam, Stephen Barstow Long

This study shows that BEST1, a chloride channel, is directly activated by extracellular GABA, with structural and functional evidence revealing the mechanism of GABA-induced channel opening.

7 citations

humanchicken / avian

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedMar 8, 2023

Ion permeation pathway within the internal pore of P2X receptor channels

Stephanie W. Tam, Kate Huffer, Mufeng Li, Kenton Jon Swartz

The paper identifies a critical residue in P2X receptor channels that influences ion permeability through lateral fenestrations.

16 citations

protein structureexperimental assay

𝕏 PostBluesky