Cell BiologybioRxivPreprint
Modulation of collagen-binding integrins affects fibroblast activation and inhibits fibrosis
Stefan Hamelmann, Fatemeh Derakhshandeh, Tom Wagner…·Inaam A. Nakchbandi
This study shows that modulating collagen-binding integrins can reduce fibrosis by inhibiting fibroblast activation in both liver and lung models, with differing mechanisms depending on the tissue.
DOI 10.1101/2025.05.14.653428