Inaam A. Nakchbandi

The paper identifies tumor-inhibitory fibroblasts that produce fibronectin, which activates signaling pathways in neighboring cells to enhance immune response against early cancer.

This study evaluates the distribution of fibronectin isoforms in liver diseases, finding they are present in hepatocytes and fibrotic bundles, contradicting the idea they are limited to fibrotic bundles.

This study shows that modulating collagen-binding integrins can reduce fibrosis by inhibiting fibroblast activation in both liver and lung models, with differing mechanisms depending on the tissue.