Lydia Grmai

This study identifies sex-specific ATF4 expression in Drosophila fat tissue that contributes to female stress tolerance during nutrient deprivation.

This study shows ATF4 interacts with EcR to both activate and repress lipid metabolism genes in Drosophila fat body under homeostasis and stress conditions.

This study identifies Atf4 as a metabolic sensor in fat tissue that regulates oogenesis and ovulation in Drosophila by modulating yolk lipoprotein synthesis and neuropeptide secretion.

This study shows that in Drosophila, sex-specific ecdysone signaling controls gonad development through cell-autonomous hormone reception, challenging the notion that steroid hormones only regulate development in vertebrates.