Meaghan Maureen Broman

This paper develops a mouse model of chronic prostatic inflammation that mirrors human BPH by showing similar immune and fibroblast features identified through scRNA-seq.

AnnotateAnyCell reduces annotation time for histopathological images by 25% using a semi-supervised framework with active contrastive learning and human-in-the-loop feedback.

The paper links an age-associated CD8+ T cell subset to symptomatic benign prostatic hyperplasia through immune aging mechanisms.

The paper identifies lipid-rich macrophage subpopulations in BPH that correlate with prostate size and urinary symptoms.