Renee E. Vickman

Immune dysregulation in the prostates of C57BL/6Aire-/- mice mirrors that seen in human benign prostatic hyperplasia

This paper develops a mouse model of chronic prostatic inflammation that mirrors human BPH by showing similar immune and fibroblast features identified through scRNA-seq.

DGAT1 as a Racially Divergent Driver of Carcinoma-Associated Fibroblast Activation Drives Tumorigenic Pathways via ERK1/2 Signaling in Prostate Cancer.

Immune cell single-cell RNA sequencing analyses link an age-associated T cell subset to symptomatic benign prostatic hyperplasia

The paper links an age-associated CD8+ T cell subset to symptomatic benign prostatic hyperplasia through immune aging mechanisms.

Infiltrating lipid-rich macrophage subpopulations identified as a regulator of increasing prostate size in human benign prostatic hyperplasia

The paper identifies lipid-rich macrophage subpopulations in BPH that correlate with prostate size and urinary symptoms.

PROSTATE CELL HETEROGENEITY AND CXCL17 UPREGULATION IN MOUSE STEROID HORMONE IMBALANCE

This study identifies CXCL17 upregulation and macrophage subsets in mouse prostate under steroid hormone imbalance, linking them to foam cell formation and inflammation.