Author

Grant M. Shoffner

University of California, Los AngelesORCID 0000-0001-5479-4203Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Feng GuoiD· 3 shared Brian NguyeniD· 1 shared Florian BarthélémyiD· 1 shared Isaiah LittleiD· 1 shared Jianfu Chen· 1 shared Jianhui Bai· 1 shared Justin PiiD· 1 shared Kongpan Li· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Feng GuoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 8, 2026

Structural engineering of dual-targeting antisense oligonucleotides enhances exon 44 skipping for treating Duchenne muscular dystrophy

Grant M. Shoffner, Florian Barthélémy, Justin Pi…·Feng Guo

This study develops 3D-bridge antisense oligonucleotides that enhance exon 44 skipping in dystrophin mRNA, showing improved binding affinity and efficacy compared to conventional ASOs.

DOI 10.64898/2026.10.01.754576

humanexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 18, 2026

Cell-type-resolved RNP topologies reveal dynamic structural mechanisms of splicing and therapeutic targets

Jianhui Bai, Kongpan Li, Wei Zhang…·Zhipeng Lu

The paper introduces SHARCLIP to map RNA-RNA, RNA-protein, and protein-protein contacts in cells, revealing structural mechanisms of splicing and therapeutic targets.

DOI 10.64898/2026.05.17.725762

humanspatial transcriptomics

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 5, 2020

Structures of microRNA-precursor apical junctions and loops reveal non-canonical base pairs important for processing

Grant M. Shoffner, Z. Peng, Feng Guo

The paper determines the structures of human miR-precursor apical junctions and loops, revealing non-canonical base pairs that contribute to processing efficiency and stability.

5 citations

humanexperimental assay

𝕏 PostBluesky