ImmunologyEmerging Microbes & InfectionsPeer-reviewed
Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1/N2 loop of Spike N-terminal domain
Xiao Niu, Zhiqiang Li, Jing Wang…·Yunlong Cao
This study identifies ultra-potent Omicron-specific antibodies targeting the N1/N2 loop of the Spike NTD, which neutralize SARS-CoV-2 by competing with ACE2 and blocking S1 shedding, but are evaded by BA.2.86 and BA.2.87.1 sublineages.
15 citationstop 4%