Nayane dos Santos Brito Silva

The paper analyzes the genetic architecture of MS patients in the OFSEP-HD cohort, identifies ancestral clusters, and presents a synthetic dataset for data sharing.

The paper evaluates HLA imputation accuracy in admixed populations using dimension reduction, finding that custom reference panels outperform standard ones for specific genetic models.

This study presents a high-coverage whole-genome sequencing dataset of 1,171 admixed elderly Brazilians, identifying novel variants and demonstrating the utility of WGS for genomic and clinical research in underrepresented populations.

The paper examines genetic diversity at HLA loci in the MHC region, showing that while SNPs show low FST values, haplotype frequencies vary geographically, impacting bone-marrow transplantation.

The paper identifies genetic variants associated with resistance to SARS-CoV-2 infection by analyzing discordant Brazilian couples.

The paper characterizes KIR2DL4 genetic diversity in a Brazilian population, identifies new sequences, and shows ancestry influences allele frequencies.