Mingming Zhao

This study shows that β2-adrenergic receptor signaling is cardioprotective in acute oxidative stress but cardiotoxic in chronic stress, with implications for β-blocker use in cardiovascular disease.

The paper identifies a conserved postprandial metabolite, pTOS, that links nutrient intake to energy balance through a gut-brain pathway in pythons and mice, with potential relevance to humans.

The paper shows that coronary endothelial cells in mouse and human hearts initially show lineage-specific transcriptional differences but later become influenced by location, with adult cells becoming more homogeneous.

This study shows that overexpressing Dach1 in endothelial cells extends coronary arteries and improves heart function after myocardial infarction in mice.