Carel Wynand le Roux

This study shows that α-MSH reduces blood glucose in humans and non-human primates via the MC5R pathway, suggesting it as a potential target for diabetes treatment.

This study identifies rare genetic variants in obesity-related genes in a UK cohort of severe obesity patients, suggesting an oligogenic inheritance pattern and demonstrating the utility of custom genotyping arrays.

This study shows that Roux-en-Y Gastric Bypass Surgery reduces renal injury in diabetic rats by altering fibrosis, inflammation, and TGF-β pathways in the kidney.