Vadim Zhernovkov

This study identifies how IFN and mimetics prevent TB susceptibility by modulating iron metabolism and lipid peroxidation in macrophages.

This study shows MYCN inhibits TrkC-induced differentiation in neuroblastoma by disrupting PKA signaling, with implications for targeting PKA to treat high-risk cases.

The paper identifies T-cell-Macrophage interactions in ovarian cancer that may influence chemotherapeutic response by modulating T-cell exhaustion and polarization.

This study develops a method to infer physical cell-cell communication networks from scRNAseq data by identifying multiplets and using univariate linear models to predict interactions.

This study uses proteomics and immunohistochemistry to analyze tumor-immune dynamics in HGSOC, identifying mechanisms of immune escape across metastatic progression.

The paper identifies transcriptional changes from physical cell-cell interactions that predict ovarian cancer patient responses to therapy.

This study uses spatial transcriptomics and proteomics to identify dysregulated genes and proteins in placenta increta, revealing ECM degradation, immune suppression, and epithelial-mesenchymal transition promoting trophoblast invasion.

This study identifies Myc dysregulation in macrophages as a driver of TB susceptibility by linking lipid peroxidation and IFN-I pathway hyperactivity.

The paper predicts nanomaterial-induced chronic inflammation using in vitro measurements and in silico modeling by identifying mechanisms of nanomaterial cycling and quarantining in lung cells.

This study shows that Roux-en-Y Gastric Bypass Surgery reduces renal injury in diabetic rats by altering fibrosis, inflammation, and TGF-β pathways in the kidney.

This study identifies transcriptional regulatory mechanisms in mouse lung tissue exposed to carbon nanotubes using gene regulatory network analysis.