Cell BiologybioRxivPreprint
GGA2-depletion in beta cells by Enteroviruses causes Golgi acidification, premature activation of cathepsins and alters the MHC class I immunopeptidome
Klaus-Peter Knoch, Antonia Kosok, Zuzana Mariničová…·Michele Solimena
This study shows that EVs deplete GGA2 in beta cells, causing Golgi acidification and altering the MHC class I immunopeptidome through premature cathepsin activation.
1 citation