Author

Carolin Wegbrod

University Hospital Carl Gustav Carus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Anke Sönmez· 3 shared Katharina Ganß· 3 shared Klaus-Peter KnochiD· 3 shared Michele SolimenaiD· 3 shared Carla Münster· 2 shared Akshaye Pal· 1 shared Alexia CarréiD· 1 shared Andreas MülleriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCell Biology

Anke Sönmez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

pH-dependent trapping of cationic amphiphilic drugs perturbs insulin granule homeostasis

Oleksandra Topcheva, Andreas S. Mueller, Marcelo Zoccoler, Martin Neukam, Pamela L. Toledo, Katharina Ganß, Anke Sönmez, Carolin Wegbrod, Carla Münster, Klaus-Peter Knoch, Juha M. Torkko, Sofia Traikov, Michał Grzybek, Michele Solimena

This study shows that cationic amphiphilic drugs (CADs) accumulate in insulin secretory granules via pH-dependent trapping, affecting monoamine storage and pH regulation.

bioRxiv · Feb 20, 2026 · PreprintCell Biology

GGA2-depletion in beta cells by Enteroviruses causes Golgi acidification, premature activation of cathepsins and alters the MHC class I immunopeptidome

Klaus-Peter Knoch, Antonia Kosok, Zuzana Mariničová, Christiana Lekka, Inna V. Kalaidzidis, Yannis L. Kalaidzidis, Marko Barovic, Antje Petzold, Anke Sönmez, Carolin Wegbrod, Katharina Ganß, Andreas Müller, Alexia Carré, Raphaël Scharfmann, Roberto Mallone, , Michele Solimena

This study shows that EVs deplete GGA2 in beta cells, causing Golgi acidification and altering the MHC class I immunopeptidome through premature cathepsin activation.

bioRxiv · Mar 28, 2025 · PreprintCell Biology

Post-transcriptional regulation of insulin mRNA storage by G3BP1/2+ condensates in beta cells

Esteban Quezada, Jovana Vasiljević, Akshaye Pal, Carla Münster, Daniela Friedland, Eyke Schöniger, Anke Sönmez, Annika Seiler, Pascal Roch, Carolin Wegbrod, Katharina Ganß, Klaus-Peter Knoch, Nicole Kipke, Simon Alberti, Rita Nano, , Michele Solimena

The paper shows that G3BP1/2 form condensates with insulin mRNA in beta cells, which dissolve upon glucose stimulation, regulating insulin mRNA storage and translation.

bioRxiv · May 25, 2024 · PreprintMolecular Biology