Cell BiologybioRxivPreprint
An INSR-BECN1-KIAA0825 complex prevents hepatocytic insulin receptor secretion via extracellular vesicles against monogenic diabetes
Kenta Kuramoto, Min Chen, Congcong He
This study identifies an INSR-BECN1-KIAA0825 complex that regulates INSR trafficking and function in hepatocytes, revealing how its disruption leads to monogenic diabetes.
DOI 10.64898/2026.09.13.751259