Miho Asaoka

This paper demonstrates that EC-isHCR retains the features of conventional isHCR and introduces an automated probe design tool to enhance its applicability across diverse samples.

The paper shows that somatic gene silencing in Drosophila germline is essential for maintaining physical segregation from soma, preventing cell death and ensuring germline viability.

The paper identifies maternal mRNAs downregulated by Nanos in Drosophila PGCs at the blastoderm stage, prior to zygotic genome activation.