Author

Franco Onofri

IRCCS Azienda Ospedaliera MetropolitanaORCID 0000-0001-5595-0036Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:electronic health records· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Antonella MarteiD· 3 shared Adriano LamaiD· 2 shared Giovanni PiccoliiD· 2 shared Alessandra Romei· 1 shared Antonella CapuozzoiD· 1 shared Britta Johanna EickholtiD· 1 shared Caterina MontaniiD· 1 shared Christian Johannes GloeckneriD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersNeuroscience

Antonella MarteORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeuroscienceeLifePeer-reviewedAug 6, 2026

LRRK2 regulates synaptic function through modulation of actin cytoskeletal dynamics

Giulia Tombesi, Shiva N. Kompella, Giulia Favetta…·Elisa Greggio

This study shows that LRRK2 regulates synaptic function by modulating actin cytoskeletal dynamics through BDNF signaling in neurons.

DOI 10.7554/elife.95987

𝕏 PostBluesky

Cell BiologybioRxivPreprintJun 3, 2026

Sephin1 rewires proteostasis through actin-dependent signaling

Giulia Frapporti, Antonella Capuozzo, Eleonora Colombo…·Giovanni Piccoli

This study identifies sephin1's mechanism of action in proteostasis disruption by showing it binds G-actin, causes cytoskeleton misfolding, and modulates autophagy through mTORC1-TFEB and GCN2-eIF2-CHOP pathways.

DOI 10.64898/2026.04.20.719601

proteomicsexperimental assay

𝕏 PostBluesky

NeuroscienceeLifePeer-reviewedNov 23, 2021

REST/NRSF drives homeostatic plasticity of inhibitory synapses in a target-dependent fashion

Cosimo Prestigio, Daniele Ferrante, Antonella Marte…·Pietro Baldelli

This study shows REST/NRSF enhances GABAergic inhibition specifically at inhibitory-onto-excitatory synapses in response to hyperactivity, maintaining neuronal homeostasis.

29 citations

mouseelectronic health records

𝕏 PostBluesky