Author

JEFF K. DAVIES

Queen Mary University of LondonORCID 0000-0002-3192-6995Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Sarah CharrotiD· 2 shared Daniel J. PenningtoniD· 1 shared Dimitris LagosiD· 1 shared James A. Aries· 1 shared James R. BlackiD· 1 shared Jamie D. Cavenagh· 1 shared John G. GribbeniD· 1 shared Kevin LitchfieldiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Sarah CharrotORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Single-cell mass cytometry maps the evolution of immune cell signatures predictive of acute graft-versus-host disease

James A. Aries, Sarah Charrot, Symeon Theocharidis, Megha Meena, Wing-Yiu Jason Lee, Monica Escorcio Correia, Daniel J. Pennington, Jamie D. Cavenagh, John G. Gribben, JEFF K. DAVIES

The paper uses mass cytometry to identify immune cell signatures predictive of acute graft-versus-host disease (aGvHD) and shows how these signatures evolve over time.

bioRxiv · Feb 26, 2025 · PreprintImmunology

LIMD1 Loss as an Early Driver of PD-L1 Upregulation and Immune Evasion in Lung Cancer

Kunal M. Shah, Paul T. Kennedy, James R. Black, Kevin Litchfield, Krupa Thakkar, Maria F. Contreras-Gerenas, Kirsten Brooksbank, Oliver Yuan, Paul Grevitt, Sarah Charrot, JEFF K. DAVIES, Lekh N. Dahal, Dimitris Lagos, Nicholas McGranahan, Tyson V. Sharp

This study shows that LIMD1 loss in lung cancer increases PD-L1 expression, promoting immune evasion and enhancing response to immune checkpoint inhibitors.

bioRxiv · Feb 6, 2025 · PreprintCancer Biology