Alberto Carbonell

This paper shows that adding a G-C base pair upstream of DCL1 cleavage sites in amiRNA precursors increases their accumulation and gene silencing efficiency in plants.

This paper develops a transgene-free method using tobacco rattle virus to express artificial small RNAs for efficient gene silencing in plants.

The paper identifies that tryptophan-binding pockets in Arabidopsis AGO1 are essential for RDR6-dependent siRNA amplification through interactions with SGS3.

This study develops a minimal syn-tasiRNA platform in tomato for precise gene silencing and antiviral resistance without transgenes.

The paper identifies FeSOD1 as a Cu-deficiency-induced interactor of AGO1 that protects it from oxidative stress, preserving miRNA-mediated gene silencing.

This paper introduces syn-tasiR-VIGS, a virus-based RNAi method using minimal precursors to silence plant genes and vaccinate against viruses without genetic modification.

The paper investigates how mRNA structure affects miRNA cleavage in vivo using a new method in Arabidopsis thaliana, finding that target site unfolding and a downstream motif determine cleavage efficiency.