ImmunologybioRxivPreprint
Establishment of a Reverse Genetics System for the Study of Human Immune Functions in Mice
Priya Pal, Shuai Gao, Hongbo Gao…·Liang Shan
This paper establishes a method to generate humanized mice with targeted gene knockouts in the human immune system using Cas9-edited CD34+ cells.
DOI 10.1101/2025.03.26.645295