Gholamreza Azizi

This study develops a CD8 T cell-dependent model of MS and identifies differences in brain and spinal cord inflammation, showing that IFN-g and PD-1 signaling regulate CD8 T cell-mediated neuroinflammation.

This study develops a therapy for NMOSD using astrocyte-derived extracellular vesicles that reduce inflammation and disease progression in a mouse model.

The paper tracks GM-CSF expression in immune cells using reporter mice, identifying diverse sources and transient expression patterns in health and autoimmune neuroinflammation.