Author

Jonathan Lasham

University of HelsinkiORCID 0000-0001-6393-9654Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Vivek SharmaiD· 2 shared Amiel Abettan· 1 shared Amina DjurabekovaiD· 1 shared Erik EndresiD· 1 shared Georgios KolypetrisiD· 1 shared Janet VonckiD· 1 shared Luka Simsive· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBiophysics

Vivek SharmaORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintOct 4, 2026

Conformational dynamics of ND2 antiporter-like subunit in intact and truncated complex I

Amiel Abettan, Jonathan Lasham, Erik Endres, Vivek Sharma

This study uses molecular dynamics simulations to investigate conformational changes in the ND2 subunit of complex I, revealing a previously unobserved structural transition linked to proton pumping.

DOI 10.64898/2026.10.02.756245

experimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintJul 14, 2026

Fast prediction of acidic amino acid sidechain conformations for cryo-EM modeling

Georgios Kolypetris, Amina Djurabekova, Jonathan Lasham…·Vivek Sharma

The paper develops a workflow to predict sidechain conformations of acidic amino acids in cryo-EM maps, validated through Q-score and molecular dynamics simulations.

DOI 10.64898/2026.07.12.738023

cryo-EMdeep learning

𝕏 PostBluesky