NeuroscienceScientific ReportsPeer-reviewed
Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs)
Jennifer N. Rauch, John Jing-Wei Chen, Alexander W. Sorum…·Kenneth S. Kosik
The paper identifies 6-O-sulfation on heparan sulfate proteoglycans as critical for tau internalization and shows it regulates uptake in multiple cell models.