Author

Wibke E. Diederich

Philipps University of MarburgORCID 0000-0001-5671-6575Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Alicia Isabel Pérez‐LorenteiD· 1 shared Allegra T. AroniD· 1 shared Anke WerneriD· 1 shared Anthony John O’DonoghueiD· 1 shared Barbara Fritz· 1 shared Berenike C. WagneriD· 1 shared Bernhard Wilke· 1 shared C. Benjamin NamaniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperSystems Biology

Alicia Isabel Pérez‐LorenteORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintMay 3, 2025

Discovery of an Antiviral PROTAC Targeting the SARS-CoV-2 Main Protease Using an Allosteric Warhead

Christopher Veeck, Lennart Laube, Anke Werner…·Stephan Becker

This study develops an antiviral PROTAC targeting SARS-CoV-2 MPro using an allosteric warhead, showing LLP019 can degrade MPro and inhibit viral variants in infected cells.

2 citations

humanexperimental assay

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Systems BiologyNature CommunicationsPeer-reviewedAug 8, 2022

Native Metabolomics Identifies the Rivulariapeptolide Family of Protease Inhibitors

Raphael Reher, Allegra T. Aron, Pavla Fajtová…·Daniel Petras

This study uses native metabolomics to identify a family of protease inhibitors from cyanobacteria, revealing their structure and potent biological activity.

53 citationstop 1%

metabolomicsexperimental assay

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Molecular BiologybioRxivPreprintJul 2, 2019

PPARβ/δ recruits NCOR and regulates transcription reinitiation

Nathalie Legrand, Clemens L. Bretscher, Svenja Zielke…·Till Adhikary

This study investigates how PPARβ/δ inverse agonists repress transcription by recruiting NCOR and interfering with transcription factor recruitment.

DOI 10.1101/525576

humanstatistical model

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