Anke Werner

This study investigates how mutations at the oligomerization interface of Sudan virus VP40 affect its structural properties and functional roles in viral RNA synthesis and budding.

This study shows that SUDV infection in IFNAR-/- mice leads to systemic viral spread and a cytokine storm, supporting their use as a model for filovirus research.

This study compares two mouse models of CCHFV infection, showing strain-specific disease severity and viral dissemination, supporting their use for antiviral research.

This paper identifies Sec61β as essential for proteolytic processing and cell entry of Marburg virus glycoprotein, unlike Ebola virus, and suggests Sec61 as a therapeutic target.

This study develops an antiviral PROTAC targeting SARS-CoV-2 MPro using an allosteric warhead, showing LLP019 can degrade MPro and inhibit viral variants in infected cells.