Molecular BiologyNucleic Acids ResearchPeer-reviewed
SLFN11-mediated tRNA regulation induces cell death by disrupting proteostasis in response to DNA-damaging agents
Yuki Iimori, Teppei Morita, Takeshi Masuda…·Akio Kanai
This study shows SLFN11 induces cell death by cleaving tRNALeu(TAA), causing ER stress and disrupting proteostasis in response to DNA-damaging agents.
7 citations