Author

Atsuo T. Sasaki

Keio UniversityORCID 0000-0003-2963-4501Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Akio KanaiiD· 1 shared Antonis E. KoromilasiD· 1 shared Brajendra K. TripathiiD· 1 shared Carlos R. Azpilcueta‐NicolasiD· 1 shared Christopher B. MarshalliD· 1 shared Douglas R. LowyiD· 1 shared Hyun-Ro Lee· 1 shared Hyungdong KimiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Akio KanaiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 10, 2025

eIF2B Selectively Anchors and Activates Mutant KRAS

Hyungdong Kim, Shiqi Diao, Kwang‐Jin Cho…·Antonis E. Koromilas

This paper shows eIF2B activates mutant KRAS by forming a complex with SOS at the plasma membrane and regulating glycosphingolipid biosynthesis.

DOI 10.1101/2025.11.10.686860

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedAug 1, 2025

SLFN11-mediated tRNA regulation induces cell death by disrupting proteostasis in response to DNA-damaging agents

Yuki Iimori, Teppei Morita, Takeshi Masuda…·Akio Kanai

This study shows SLFN11 induces cell death by cleaving tRNALeu(TAA), causing ER stress and disrupting proteostasis in response to DNA-damaging agents.

7 citations

humanproteomics

𝕏 PostBluesky