Genetically determining individualized clinical reference ranges for the biomarker tryptase can limit unnecessary procedures and unmask myeloid neoplasms
Jack F. Chovanec, Ilker Tunc, Jason Hughes…·Jonathan J. Lyons
This study determines individualized tryptase reference ranges by modeling BST levels based on TPSAB1 copy number, showing that elevated levels can indicate clonal myeloid neoplasms or be normal in HT carriers.