Nazmul Haque

The paper introduces a method to infer isoform-level kinetics of nonsense-mediated mRNA decay using short-read NR-seq data, revealing variability in NMD efficiency and decay rates of transcripts with and without PTCs.

This study identifies a network of DZF proteins that regulate alternative splicing through dsRNA binding and reveals their roles in splicing fidelity and cassette exon regulation.

The paper shows that NMD regulates alternative polyadenylation products by preferentially targeting long 3UTRs and that PTBP1 modulates this process.