Michael M. Seidman

The paper introduces a bifunctional antibody conjugate to mark the location of DNA binding proteins relative to DSBs on deproteinized DNA fibers.

This paper shows that the TONSL-MMS22L complex and FANCM form an interdependent chromatin complex to resolve replication stress and improve cancer prognosis.

The paper identifies two distinct replisomes, one associated with DONSON in early S phase and euchromatin, and another with FANCM in late S phase and heterochromatin.