BiophysicsbioRxivPreprint
DNA binding drives phase separation of the Gcn4 bZIP domain and reveals its conformational ensemble in the diluted and condensate phases
Antonino Caliò, Florian Turbant, Mark D. Tully…·Annalisa Pastore
1 citation
Author
Satyan Sharma
Uppsala UniversityORCID 0000-0001-5732-7002Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagResearch Focus:protein folding & dynamics· 2Research Focus:cell signaling & trafficking· 1Research Focus:chromatin & epigenetic regulation· 1Approach:experimental assay· 1Approach:mechanistic / dynamical model· 1Approach:simulation· 1Assay:structural biology· 1Research Focus:synaptic & neural circuits· 1
Activity by Year
2025-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 16 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 papers
Recent·Most cited
- BiophysicsBiophysical JournalPeer-reviewed
Syntaxin 1A Transmembrane Domain Palmitoylation Induces a Fusogenic Conformation
Dong An, Satyan Sharma, Manfred Lindau
This study uses molecular dynamics simulations to show that Stx1A TMD palmitoylation stabilizes its conformation, facilitates SNARE complex formation, and modulates fusion pore dynamics during neurotransmitter release.
- BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
Caveolin assemblies displace one bilayer leaflet to organize and bend membranes
Milka Doktorova, Sebastian Daum, Tyler R. Reagle…·Ilya Levental
This paper investigates how the CAV1-8S caveolin complex interacts with lipid membranes through a novel leaflet replacement mechanism, revealing its role in membrane curvature and organization.
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