Alon M. Douek

This paper identifies Ca2+-mediated protein citrullination as a regulator of neural stem cell proliferation in CNS regeneration and cancer, showing PAD inhibitors suppress medulloblastoma growth.

The paper uses a zebrafish model of MPS IIIA to identify synaptic activity deficiencies as a key driver of disease progression through systems-level omics analyses and a novel bioinformatic tool.

This study develops a zebrafish model for CDKL5 Deficiency Disorder to investigate disease mechanisms and screen for therapies.

This study identifies two phases of cellular regeneration after spinal cord injury in zebrafish, highlighting the role of precursor neuron migration in initiating functional recovery.

This study uses a zebrafish model of familial Alzheimer’s disease to show accelerated brain aging and transcriptional inversion linked to glucocorticoid resistance and immune pathway changes before histopathology.

This study investigates the regenerative capacity of quiescent radial-glial stem cells in the zebrafish tectum, showing that lesion-induced proliferation and neurogenesis occur through distinct progenitor populations and are Wnt-independent.