BiochemistrybioRxivPreprint
Discovery of a novel stereospecific β-hydroxyacyl-CoA lyase/thioesterase shared by three metabolic pathways in Mycobacterium tuberculosis
Hua Wang, Alexander A. Fedorov, Elena V. Fedorov…·Luiz Pedro S. de Carvalho
This study identifies Rv2498c as a multi-functional β-hydroxyacyl-CoA lyase/thioesterase in Mtb involved in three metabolic pathways and shows its deletion attenuates Mtb in a mouse model.
DOI 10.1101/322404