Aakanksha Singhvi

The paper identifies molecular subcategories of C. elegans glia across sexes using single nuclear RNA-seq and machine learning, revealing sex-specific heterogeneity and alternative neuromodulator processing mechanisms.

The paper shows glia compartmentalize regulatory cues into microdomains around specific neurons, with KCC-3 localization dependent on neuron cilia and aging.

The paper shows epithelial cells maintain glial and neuron shapes by resisting mechanical stress through a conserved molecular pathway involving UNC-23/BAG2.

This study shows that glia actively engulf neuron fragments in C. elegans, affecting neuron shape and thermosensory behavior through a molecular pathway involving PS receptors and GTPase signaling.