Author

Maria D. Purice

Fred Hutch Cancer CenterORCID 0000-0003-2756-7763Unclaimed ORCID profile · follow to get notified of new preprints

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Organism:C. elegans· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:protein structure prediction· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Aakanksha SinghviiD· 1 shared Amanda JeffersoniD· 1 shared Elgene J. A. QuitevisiD· 1 shared Hannah LongiD· 1 shared Katherine S. LehmanniD· 1 shared Liza J. SeversiD· 1 shared M. A. FreemaniD· 1 shared Manu N. SettyiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

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10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Aakanksha SinghviORCID

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2 papers

Recent·Most cited

BiochemistryNaturePeer-reviewedApr 23, 2025

Structural basis of bulk lipid transfer by bridge-like lipid transfer protein LPD-3

Yunsik Kang, Katherine S. Lehmann, Hannah Long…·Sarah Clark

This study determines the structure of the LPD-3 BLTP complex and reveals its mechanism for bulk lipid transfer through interactions with Intake and Spigot proteins.

32 citationstop 1%

C. eleganscryo-EM

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 21, 2023

Molecular heterogeneity of C. elegans glia across sexes

Maria D. Purice, Elgene J. A. Quitevis, R. Sean Manning…·Aakanksha Singhvi

The paper identifies molecular subcategories of C. elegans glia across sexes using single nuclear RNA-seq and machine learning, revealing sex-specific heterogeneity and alternative neuromodulator processing mechanisms.

12 citations

C. elegansscRNA-seq

𝕏 PostBluesky