Joshua LaBaer

This study shows that SETD6 methylates RAD18, affecting its localization and reducing DNA damage.

The paper introduces Mx-MeDIP-Seq, a method for analyzing DNA methylation using small DNA samples, showing high correlation and efficiency compared to traditional methods.

This paper develops a highly sensitive and multiplexed in situ protein profiling method using click chemistry and cleavable fluorophores, enabling the quantification of 28 proteins in FFPE tissue and classification of over 820,000 cells.

This paper introduces a highly sensitive in situ proteomics method using cleavable fluorescent tyramide and antibodies, enabling detailed analysis of protein expression in human tissues.

This paper introduces a method for highly sensitive and multiplexed in situ protein profiling using cleavable fluorescent streptavidin and biotin conjugated antibodies, achieving 10-fold improved sensitivity over existing methods.

The paper demonstrates that adding tandem histone-binding domains to a synthetic chromatin effector enhances its activity in gene activation.